In situ        111In-doping for achieving biocompatible and non-leachable 111In-labeled Fe3O4 nanoparticles

Jianfeng Zeng; Bing Jia; Ruirui Qiao; Chao Wang; Lihong Jing; Fan Wang; Mingyuan Gao

doi:10.1039/C3CC48948E

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In situ¹¹¹In-doping for achieving biocompatible and non-leachable ¹¹¹In-labeled Fe₃O₄ nanoparticles†

Jianfeng Zeng,^a Bing Jia,^b Ruirui Qiao,^a Chao Wang,^b Lihong Jing,^a Fan Wang^b and Mingyuan Gao*^a

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* Corresponding authors

^a Institute of Chemistry, Chinese Academy of Sciences, Bei Yi Jie 2, Zhong Guan Cun, Beijing 100190, China
E-mail: gaomy@iccas.ac.cn
Web: www.gaomingyuan.com
Fax: +86 10 8261 3214

^b Medical Isotopes Research Center, Peking University, Xueyuan Road 38, Beijing 100191, China

Abstract

The present study reports a new approach for synthesizing ¹¹¹In-radiolabeled biocompatible Fe₃O₄ nanoparticles. Radioactive ¹¹¹In is doped in situ into the lattice of Fe₃O₄ nanoparticles to achieve robust radiolabeling for accurately tracing PEGylated Fe₃O₄ particles in vivo.

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Article information

DOI: https://doi.org/10.1039/C3CC48948E
Article type: Communication
Submitted: 23 Nov 2013
Accepted: 16 Dec 2013
First published: 02 Jan 2014

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Chem. Commun., 2014,50, 2170-2172

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In situ ¹¹¹In-doping for achieving biocompatible and non-leachable ¹¹¹In-labeled Fe₃O₄ nanoparticles

J. Zeng, B. Jia, R. Qiao, C. Wang, L. Jing, F. Wang and M. Gao, Chem. Commun., 2014, 50, 2170 DOI: 10.1039/C3CC48948E

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