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Issue 13, 2014
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A T7 exonuclease-assisted cyclic enzymatic amplification method coupled with rolling circle amplification: a dual-amplification strategy for sensitive and selective microRNA detection

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Abstract

A T7 exonuclease-assisted cyclic enzymatic amplification method (CEAM) was combined with rolling circle amplification (RCA) to develop a RCA–CEAM dual amplification method for ultrasensitive detection of microRNA with excellent selectivity.

Graphical abstract: A T7 exonuclease-assisted cyclic enzymatic amplification method coupled with rolling circle amplification: a dual-amplification strategy for sensitive and selective microRNA detection

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Publication details

The article was received on 14 Nov 2013, accepted on 05 Dec 2013 and first published on 05 Dec 2013


Article type: Communication
DOI: 10.1039/C3CC48707E
Citation: Chem. Commun., 2014,50, 1576-1578
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    A T7 exonuclease-assisted cyclic enzymatic amplification method coupled with rolling circle amplification: a dual-amplification strategy for sensitive and selective microRNA detection

    L. Cui, Z. Zhu, N. Lin, H. Zhang, Z. Guan and C. J. Yang, Chem. Commun., 2014, 50, 1576
    DOI: 10.1039/C3CC48707E

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