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Ultrasensitive detection of thrombin using surface plasmon resonance and quartz crystal microbalance sensors by aptamer-based rolling circle amplification and nanoparticle signal enhancement

Peng He,a   Lijun Liu,a   Wenping Qiaoa and   Shusheng Zhang*b  
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a
Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P.R. China
b
College of Chemistry and Chemical Engineering, Linyi University, Linyi 276005, P.R. China
E-mail: shushzhang@126.com;
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Chem. Commun., 2014,50, 1481-1484

DOI: 10.1039/C3CC48223E
Received 27 Oct 2013, Accepted 27 Nov 2013
First published online 28 Nov 2013
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