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Issue 8, 2014
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Enzyme-free fluorescent-amplified aptasensors based on target-responsive DNA strand displacement via toehold-mediated click chemical ligation

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Abstract

A new target-responsive DNA strand displacement system via toehold-mediated click chemical ligation was designed and prepared for enzyme-free fluorescent-amplified aptasensors. The aptasensors significantly amplified fluorescent signals in response to targets based on target recycling processes.

Graphical abstract: Enzyme-free fluorescent-amplified aptasensors based on target-responsive DNA strand displacement via toehold-mediated click chemical ligation

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Publication details

The article was received on 21 Oct 2013, accepted on 15 Nov 2013, published on 18 Nov 2013 and first published online on 18 Nov 2013


Article type: Communication
DOI: 10.1039/C3CC48064J
Citation: Chem. Commun., 2014,50, 991-993
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    Enzyme-free fluorescent-amplified aptasensors based on target-responsive DNA strand displacement via toehold-mediated click chemical ligation

    M. Oishi, S. Nakao and D. Kato, Chem. Commun., 2014, 50, 991
    DOI: 10.1039/C3CC48064J

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