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Issue 14, 2014
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Five-plex isotope dimethyl labeling for quantitative proteomics

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Abstract

Stable isotope dimethyl labeling, a widely used method for quantitative proteomics, was extended to five channels for the first time. Comprehensive proteome and phosphoproteome quantification validated the high quantification accuracy and throughput of this five-plex method.

Graphical abstract: Five-plex isotope dimethyl labeling for quantitative proteomics

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Publication details

The article was received on 17 Oct 2013, accepted on 06 Dec 2013 and first published on 09 Dec 2013


Article type: Communication
DOI: 10.1039/C3CC47998F
Citation: Chem. Commun., 2014,50, 1708-1710
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    Five-plex isotope dimethyl labeling for quantitative proteomics

    Y. Wu, F. Wang, Z. Liu, H. Qin, C. Song, J. Huang, Y. Bian, X. Wei, J. Dong and H. Zou, Chem. Commun., 2014, 50, 1708
    DOI: 10.1039/C3CC47998F

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