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Issue 2, 2014
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Label-free and ultrasensitive fluorescence detection of cocaine based on a strategy that utilizes DNA-templated silver nanoclusters and the nicking endonuclease-assisted signal amplification method

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Abstract

A general and reliable strategy for the detection of cocaine was proposed utilizing DNA-templated silver nanoclusters as signal indicators and the nicking endonuclease-assisted signal amplification method. This strategy can detect cocaine specifically with a detection limit as low as 2 nM by using a small volume of 5 μL.

Graphical abstract: Label-free and ultrasensitive fluorescence detection of cocaine based on a strategy that utilizes DNA-templated silver nanoclusters and the nicking endonuclease-assisted signal amplification method

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Publication details

The article was received on 28 Sep 2013, accepted on 23 Oct 2013 and first published on 24 Oct 2013


Article type: Communication
DOI: 10.1039/C3CC47418F
Citation: Chem. Commun., 2014,50, 180-182
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    Label-free and ultrasensitive fluorescence detection of cocaine based on a strategy that utilizes DNA-templated silver nanoclusters and the nicking endonuclease-assisted signal amplification method

    K. Zhang, K. Wang, X. Zhu, J. Zhang, L. Xu, B. Huang and M. Xie, Chem. Commun., 2014, 50, 180
    DOI: 10.1039/C3CC47418F

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