Issue 8, 2014
From the journal:

Chemical Communications

DNA strand-displacement-induced fluorescence enhancement for highly sensitive and selective assay of multiple microRNA in cancer cells†

Ping Wu,a   Yunqiu Tu,a   Yingdan Qian,a   Hui Zhanga  and  Chenxin Cai*a  

* Corresponding authors

a Jiangsu Key Laboratory of New Power Batteries, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, P. R. China
E-mail: cxcai@njnu.edu.cn
Fax: +86 25 85891767
Tel: +86 25 85891780

Abstract

We report a new strategy for evaluating multiple miRNA expressions in cancer cells based on DNA strand-displacement-induced fluorescence enhancement. This assay has the ability to discriminate the target from even single-base mismatched sequences or other miRNAs.

Graphical abstract: DNA strand-displacement-induced fluorescence enhancement for highly sensitive and selective assay of multiple microRNA in cancer cells

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC46773B
Article type
Communication
Submitted
05 Sep 2013
Accepted
18 Nov 2013
First published
19 Nov 2013

Chem. Commun., 2014,50, 1012-1014

Permissions

Request permissions

DNA strand-displacement-induced fluorescence enhancement for highly sensitive and selective assay of multiple microRNA in cancer cells

P. Wu, Y. Tu, Y. Qian, H. Zhang and C. Cai, Chem. Commun., 2014, 50, 1012 DOI: 10.1039/C3CC46773B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements