Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 95, 2013
Previous Article Next Article

Trifluoromethyl ketones: properties, preparation, and application

Author affiliations

Abstract

Trifluoromethyl ketones (TFMKs) are exceedingly valuable synthetic targets in their own right and as synthons in the construction of fluorinated pharmacons. This Feature Article provides an overview of the properties of TFMKs, an in-depth discussion of the methods available for their synthesis, and two illustrative examples of their application as key intermediates in medicinal chemistry.

Graphical abstract: Trifluoromethyl ketones: properties, preparation, and application

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 15 Aug 2013, accepted on 11 Oct 2013 and first published on 14 Oct 2013


Article type: Feature Article
DOI: 10.1039/C3CC46266H
Citation: Chem. Commun., 2013,49, 11133-11148
  •   Request permissions

    Trifluoromethyl ketones: properties, preparation, and application

    C. B. Kelly, M. A. Mercadante and N. E. Leadbeater, Chem. Commun., 2013, 49, 11133
    DOI: 10.1039/C3CC46266H

Search articles by author