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Issue 3, 2014
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Diastereoselective α-C–H functionalization of aliphatic N-heterocycles: an efficient route to ring fused oxazines

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Abstract

A novel method for direct C–H functionalization of saturated N-heterocycles allowing easy access to synthetically as well as biologically important and structurally diverse ring-fused oxazines is developed. The method is operationally simple and highly diastereoselective. Moreover, it is efficient in functionalizing broad classes of both cyclic and acyclic amines including the substrates that are otherwise difficult to functionalize.

Graphical abstract: Diastereoselective α-C–H functionalization of aliphatic N-heterocycles: an efficient route to ring fused oxazines

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Publication details

The article was received on 13 Aug 2013, accepted on 24 Oct 2013 and first published on 28 Oct 2013


Article type: Communication
DOI: 10.1039/C3CC46191B
Citation: Chem. Commun., 2014,50, 332-334
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    Diastereoselective α-C–H functionalization of aliphatic N-heterocycles: an efficient route to ring fused oxazines

    S. Mahato, S. Haldar and C. K. Jana, Chem. Commun., 2014, 50, 332
    DOI: 10.1039/C3CC46191B

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