Issue 93, 2013
From the journal:

Chemical Communications

A multicomponent cascade reaction for the synthesis of novel chromenopyranpyrazole scaffolds†‡

Manickam Bakthadoss,*ab   Damodharan Kannana  and  Raman Selvakumara  

* Corresponding authors

a Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai – 600 025, Tamilnadu, India
Fax: +91-44-22352494

b Department of Chemistry, Pondicherry University, R. V. Nagar, Pondicherry – 605 014, India
E-mail: bhakthadoss@yahoo.com

Abstract

A catalyst, solvent, work-up and column free synthesis of chromenopyranpyrazoles via multicomponent cascade reaction has been achieved with high stereoselectivity. This novel reaction creates two N–C, two C–C and one O–C bonds through a domino process for the construction of three new rings and three contiguous stereogenic centers.

Graphical abstract: A multicomponent cascade reaction for the synthesis of novel chromenopyranpyrazole scaffolds

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Article information

DOI
https://doi.org/10.1039/C3CC45502E
Article type
Communication
Submitted
19 Jul 2013
Accepted
19 Sep 2013
First published
19 Sep 2013

Chem. Commun., 2013,49, 10947-10949

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A multicomponent cascade reaction for the synthesis of novel chromenopyranpyrazole scaffolds

M. Bakthadoss, D. Kannan and R. Selvakumar, Chem. Commun., 2013, 49, 10947 DOI: 10.1039/C3CC45502E

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