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Asymmetric synthesis of 3-spirocyclopropyl-2-oxindoles via intramolecular trapping of chiral aza-ortho-xylylene

Xiaowei Dou,a   Weijun Yao,a   Bo Zhoua and   Yixin Lu*a  
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a
Department of Chemistry and Medicinal Chemistry Program, Life Sciences Institute, National University of Singapore, 3 Science Drive 3, Republic of Singapore
E-mail: chmlyx@nus.edu.sg
Chem. Commun., 2013,49, 9224-9226

DOI: 10.1039/C3CC45369C
Received 16 Jul 2013, Accepted 08 Aug 2013
First published online 08 Aug 2013
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