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Issue 88, 2013
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Design, synthesis and evaluation of a boronic acid based artificial receptor for L-DOPA in aqueous media

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Abstract

Design and synthesis of a boronic acid based artificial receptor which selectively and effectively bound to a neurotransmitter, L-DOPA (1), in aqueous media. In addition, the synthetic receptor was found to effectively inhibit the DDC (L-DOPA decarboxylase) enzymatic reaction under physiological conditions.

Graphical abstract: Design, synthesis and evaluation of a boronic acid based artificial receptor for l-DOPA in aqueous media

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Publication details

The article was received on 12 Jul 2013, accepted on 16 Sep 2013 and first published on 17 Sep 2013


Article type: Communication
DOI: 10.1039/C3CC45275A
Citation: Chem. Commun., 2013,49, 10403-10405
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    Design, synthesis and evaluation of a boronic acid based artificial receptor for L-DOPA in aqueous media

    H. Ueno, T. Iwata, N. Koshiba, D. Takahashi and K. Toshima, Chem. Commun., 2013, 49, 10403
    DOI: 10.1039/C3CC45275A

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