Acid-cleavable thiomaleamic acid linker for homogeneous antibody–drug conjugation†
Abstract
In this communication we describe a novel acid-cleavable linker strategy for antibody–
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* Corresponding authors
a
Department of Chemistry, University College London, 20 Gordon Street, London, UK
E-mail:
m.e.b.smith@ucl.ac.uk, vpenterprise@ucl.ac.uk
Tel: +44 (0)20 7679 7538
b UCL Cancer Institute, 72 Huntley Street, London, UK
In this communication we describe a novel acid-cleavable linker strategy for antibody–
L. Castañeda, A. Maruani, F. F. Schumacher, E. Miranda, V. Chudasama, K. A. Chester, J. R. Baker, M. E. B. Smith and S. Caddick, Chem. Commun., 2013, 49, 8187 DOI: 10.1039/C3CC45220D
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