Issue 78, 2013

Development of an expedient intramolecular Pauson–Khand reaction approach to stereoselectively construct the trans-decalin with a C1 quaternary chiral center

Abstract

Stereoselective synthesis of the trans-decalin subunit with a defined C1 quaternary chiral center has been achieved by the Pauson–Khand reaction (PKR) as a key step. The developed chemistry offers an alternative to the IMDA reaction that has been used for the syntheses of trans-decalin based biologically active natural products.

Graphical abstract: Development of an expedient intramolecular Pauson–Khand reaction approach to stereoselectively construct the trans-decalin with a C1 quaternary chiral center

Supplementary files

Article information

Article type
Communication
Submitted
11 Jul 2013
Accepted
31 Jul 2013
First published
01 Aug 2013

Chem. Commun., 2013,49, 8806-8808

Development of an expedient intramolecular Pauson–Khand reaction approach to stereoselectively construct the trans-decalin with a C1 quaternary chiral center

L. Shi, H. Shen, L. Fang, J. Huang, C. Li and Z. Yang, Chem. Commun., 2013, 49, 8806 DOI: 10.1039/C3CC45170D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements