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Issue 82, 2013
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G-quadruplex unfolding in higher-order DNA structures

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Abstract

G-quadruplex unfolding within a sequence of two quadruplex units was characterized by gel electrophoresis, calorimetry and spectroscopy. The obtained results suggest that the kinetics and thermodynamics of the individual quadruplex unfolding are affected by its interaction with other DNA secondary structural elements.

Graphical abstract: G-quadruplex unfolding in higher-order DNA structures

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Publication details

The article was received on 18 Jun 2013, accepted on 16 Aug 2013 and first published on 19 Aug 2013


Article type: Communication
DOI: 10.1039/C3CC44560G
Citation: Chem. Commun., 2013,49, 9488-9490
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    G-quadruplex unfolding in higher-order DNA structures

    I. Fotticchia, C. Giancola and L. Petraccone, Chem. Commun., 2013, 49, 9488
    DOI: 10.1039/C3CC44560G

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