Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 73, 2013
Previous Article Next Article

Iron-catalyzed asymmetric haloamination reactions

Author affiliations

Abstract

The first iron(III)/N,N′-dioxide-catalyzed asymmetric haloamination of 3-alkylidene- and 3-arylidene-indolin-2-ones was developed, affording the corresponding chiral oxindole derivatives bearing vicinal haloamine substituents with excellent results (up to 99% yield, 99% ee, >19 : 1 dr). This iron catalyst also exhibits perfect enantioselectivity for chalcone derivatives. The cooperative activation of the substrate and the reagent in concert guarantees the high stereoselectivity.

Graphical abstract: Iron-catalyzed asymmetric haloamination reactions

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 12 Jun 2013, accepted on 05 Jul 2013 and first published on 01 Aug 2013


Article type: Communication
DOI: 10.1039/C3CC44421J
Citation: Chem. Commun., 2013,49, 8054-8056
  •   Request permissions

    Iron-catalyzed asymmetric haloamination reactions

    Y. Cai, X. Liu, P. Zhou, Y. Kuang, L. Lin and X. Feng, Chem. Commun., 2013, 49, 8054
    DOI: 10.1039/C3CC44421J

Search articles by author