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Issue 75, 2013
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Selective fluorescent-free detection of biomolecules on nanobiochips by wavelength dependent-enhanced dark field illumination

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Abstract

Individual silver nanoparticle-conjugated target protein (cTnI) molecules on gold-nanopatterned chip were selectively detected by wavelength dependent-enhanced dark field illumination. Using specific nanoparticles with unique sizes and materials, the immunotargeted nanoparticle on the chips was detected at the single-molecule level by monitoring changes in the plasmonic resonance based on wavelength dependence.

Graphical abstract: Selective fluorescent-free detection of biomolecules on nanobiochips by wavelength dependent-enhanced dark field illumination

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Publication details

The article was received on 03 Jun 2013, accepted on 18 Jul 2013 and first published on 18 Jul 2013


Article type: Communication
DOI: 10.1039/C3CC44153A
Citation: Chem. Commun., 2013,49, 8335-8337
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    Selective fluorescent-free detection of biomolecules on nanobiochips by wavelength dependent-enhanced dark field illumination

    S. Lee, H. Yu and S. H. Kang, Chem. Commun., 2013, 49, 8335
    DOI: 10.1039/C3CC44153A

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