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Issue 68, 2013
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Metal-free oxidative hydroxyalkylarylation of activated alkenes by direct sp3 C–H functionalization of alcohols

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Abstract

A metal-free tandem radical addition/cyclization reaction of activated alkenes and alcohols has been developed. The process provides an efficient and atom economical access to various valuable hydroxyl-containing oxindoles through the direct sp3 C–H functionalization of alcohols.

Graphical abstract: Metal-free oxidative hydroxyalkylarylation of activated alkenes by direct sp3 C–H functionalization of alcohols

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Publication details

The article was received on 30 May 2013, accepted on 27 Jun 2013 and first published on 28 Jun 2013


Article type: Communication
DOI: 10.1039/C3CC44055A
Citation: Chem. Commun., 2013,49, 7540-7542
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    Metal-free oxidative hydroxyalkylarylation of activated alkenes by direct sp3 C–H functionalization of alcohols

    Y. Meng, L. Guo, H. Wang and X. Duan, Chem. Commun., 2013, 49, 7540
    DOI: 10.1039/C3CC44055A

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