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Issue 74, 2013
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The force of transporting a single amino acid into the living cell measured using atomic force microscopy

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Abstract

We used single molecule force spectroscopy (SMFS) to investigate the interacting force between single cysteine and amino acid transporters in eukaryotic cell membranes. We measured the transporting force of cysteine and found that its conformation on the AFM tip is important for discriminating the substrate in the transporting pathway.

Graphical abstract: The force of transporting a single amino acid into the living cell measured using atomic force microscopy

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Publication details

The article was received on 20 May 2013, accepted on 17 Jul 2013, published on 17 Jul 2013 and first published online on 17 Jul 2013


Article type: Communication
DOI: 10.1039/C3CC43779E
Citation: Chem. Commun., 2013,49, 8163-8165
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    The force of transporting a single amino acid into the living cell measured using atomic force microscopy

    X. Shang, Y. Shan, Y. Pan, M. Cai, J. Jiang and H. Wang, Chem. Commun., 2013, 49, 8163
    DOI: 10.1039/C3CC43779E

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