Jump to main content
Jump to site search

Issue 56, 2013
Previous Article Next Article

Glutathione-complexed iron–sulfur clusters. Reaction intermediates and evidence for a template effect promoting assembly and stability

Author affiliations

Abstract

Assembly and stabilization of a glutathione-complexed [2Fe–2S] cluster is promoted by aggregation of glutathione. The cluster core selects the tetramer species from a collection of equilibrating solution aggregate species, and in turn the core is stabilized toward hydrolytic degradation. Studies of glutathione derivatives, in combination with mass spectrometric and Mössbauer investigations provide insight on reaction intermediates during formation of [2Fe–2S](GS)42−.

Graphical abstract: Glutathione-complexed iron–sulfur clusters. Reaction intermediates and evidence for a template effect promoting assembly and stability

Back to tab navigation

Supplementary files

Publication details

The article was received on 14 May 2013, accepted on 29 May 2013 and first published on 29 May 2013


Article type: Communication
DOI: 10.1039/C3CC43620A
Citation: Chem. Commun., 2013,49, 6313-6315
  •   Request permissions

    Glutathione-complexed iron–sulfur clusters. Reaction intermediates and evidence for a template effect promoting assembly and stability

    W. Qi, J. Li, C. Y. Chain, G. A. Pasquevich, A. F. Pasquevich and J. A. Cowan, Chem. Commun., 2013, 49, 6313
    DOI: 10.1039/C3CC43620A

Search articles by author

Spotlight

Advertisements