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Issue 77, 2013
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One-pot one-step deracemization of amines using ω-transaminases

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Abstract

In this study, we developed a one-pot one-step deracemization method for the production of various enantiomerically pure amines using two opposite enantioselective ω-TAs. Using this method, various aromatic amines were successfully converted to their (R)-forms (>99%) with good conversion.

Graphical abstract: One-pot one-step deracemization of amines using ω-transaminases

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Publication details

The article was received on 06 May 2013, accepted on 11 Jun 2013 and first published on 11 Jun 2013


Article type: Communication
DOI: 10.1039/C3CC43348J
Citation: Chem. Commun., 2013,49, 8629-8631
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    One-pot one-step deracemization of amines using ω-transaminases

    G. Shin, S. Mathew, M. Shon, B. Kim and H. Yun, Chem. Commun., 2013, 49, 8629
    DOI: 10.1039/C3CC43348J

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