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Issue 58, 2013
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Electrochemical synthesis of azanucleoside derivatives using a lithium perchlorate–nitromethane system

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Abstract

We have developed a highly efficient synthetic method for azanucleosides using a lithium perchlorate–nitromethane reaction medium, allowing direct and exclusive installation of various nucleophiles, including protected nucleobases into prolinol derivatives at the preferred 5-position.

Graphical abstract: Electrochemical synthesis of azanucleoside derivatives using a lithium perchlorate–nitromethane system

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Publication details

The article was received on 03 May 2013, accepted on 26 May 2013 and first published on 30 May 2013


Article type: Communication
DOI: 10.1039/C3CC43273D
Citation: Chem. Commun., 2013,49, 6525-6527
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    Electrochemical synthesis of azanucleoside derivatives using a lithium perchlorate–nitromethane system

    S. Kim, T. Shoji, Y. Kitano and K. Chiba, Chem. Commun., 2013, 49, 6525
    DOI: 10.1039/C3CC43273D

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