Jump to main content
Jump to site search

Issue 76, 2013
Previous Article Next Article

Real-time monitoring of DNA hybridization kinetics on living cell surfaces

Author affiliations

Abstract

We determined hybridization rates of DNA probes bound to the surfaces of a human cell, and compared the rates with those determined in solution. The rates were slower on the cell surface than in solution-phase. The position of the nucleation site but not the location of the formed duplex relative to the cell surface adversely affected the hybridization kinetics.

Graphical abstract: Real-time monitoring of DNA hybridization kinetics on living cell surfaces

Back to tab navigation

Supplementary files

Publication details

The article was received on 23 Apr 2013, accepted on 30 May 2013 and first published on 30 May 2013


Article type: Communication
DOI: 10.1039/C3CC42990C
Citation: Chem. Commun., 2013,49, 8444-8446
  •   Request permissions

    Real-time monitoring of DNA hybridization kinetics on living cell surfaces

    A. B. Rode, T. Endoh, H. Tateishi-Karimata, S. Takahashi and N. Sugimoto, Chem. Commun., 2013, 49, 8444
    DOI: 10.1039/C3CC42990C

Search articles by author

Spotlight

Advertisements