Jump to main content
Jump to site search

Issue 52, 2013
Previous Article Next Article

Amine–N-heterocyclic carbene cascade catalysis for the asymmetric synthesis of fused indane derivatives with multiple chiral centres

Author affiliations

Abstract

An aminocatalytic asymmetric Diels–Alder reaction of 2,4-dienals and labile 1-indenones in situ generated from 3-bromo-1-indanones was developed, producing highly fused indane products with multiple chiral centres followed by a cascade N-heterocyclic carbene-mediated benzoin condensation.

Graphical abstract: Amine–N-heterocyclic carbene cascade catalysis for the asymmetric synthesis of fused indane derivatives with multiple chiral centres

Back to tab navigation

Supplementary files

Publication details

The article was received on 17 Apr 2013, accepted on 09 May 2013 and first published on 13 May 2013


Article type: Communication
DOI: 10.1039/C3CC42823K
Citation: Chem. Commun., 2013,49, 5892-5894
  •   Request permissions

    Amine–N-heterocyclic carbene cascade catalysis for the asymmetric synthesis of fused indane derivatives with multiple chiral centres

    Z. Jia, K. Jiang, Q. Zhou, L. Dong and Y. Chen, Chem. Commun., 2013, 49, 5892
    DOI: 10.1039/C3CC42823K

Search articles by author

Spotlight

Advertisements