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Issue 2, 2014
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The role of spacers on the self-assembly of DNA aptamer-amphiphiles into micelles and nanotapes

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Abstract

The self-assembly of single-stranded DNA (ssDNA) aptamer-amphiphiles was influenced by the choice of spacer used to link the hydrophobic tail and aptamer headgroup. Aptamer-amphiphiles without spacers or with hydrophilic spacers formed globular micelles while amphiphiles with hydrophobic spacers formed bilayer nanotapes, which are the first such structures formed by DNA-amphiphiles.

Graphical abstract: The role of spacers on the self-assembly of DNA aptamer-amphiphiles into micelles and nanotapes

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Publication details

The article was received on 29 Mar 2013, accepted on 26 Oct 2013 and first published on 29 Oct 2013


Article type: Communication
DOI: 10.1039/C3CC42311E
Citation: Chem. Commun., 2014,50, 210-212
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    The role of spacers on the self-assembly of DNA aptamer-amphiphiles into micelles and nanotapes

    T. R. Pearce, B. Waybrant and E. Kokkoli, Chem. Commun., 2014, 50, 210
    DOI: 10.1039/C3CC42311E

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