Jump to main content
Jump to site search

Issue 61, 2013
Previous Article Next Article

N-terminal α-amino group modification of peptides by an oxime formation–exchange reaction sequence

Author affiliations

Abstract

A site-specific and efficient method for N-terminal modification of peptides using oxone for selective oxidation of N-terminal α-amino groups of peptides to oximes followed by transoximation with O-substituted hydroxylamines has been developed.

Graphical abstract: N-terminal α-amino group modification of peptides by an oxime formation–exchange reaction sequence

Back to tab navigation

Supplementary files

Publication details

The article was received on 28 Mar 2013, accepted on 11 Jun 2013 and first published on 11 Jun 2013


Article type: Communication
DOI: 10.1039/C3CC42261E
Citation: Chem. Commun., 2013,49, 6888-6890
  •   Request permissions

    N-terminal α-amino group modification of peptides by an oxime formation–exchange reaction sequence

    K. K. Kung, K. Wong, K. Leung and M. Wong, Chem. Commun., 2013, 49, 6888
    DOI: 10.1039/C3CC42261E

Search articles by author

Spotlight

Advertisements