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Efficient synthesis of highly substituted pyrroles through a Pd(OCOCF3)2-catalyzed cascade reaction of 2-alkenal-1,3-dicarbonyl compounds with primary amines

Wei Yang,a   Liliang Huang,a   Hong Liu,a   Wei Wang*abc and   Hao Li*ab  
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a
Shanghai Institute of Materia Medica, Shanghai, P.R.China
E-mail: hli77@ecust.edu.cn;
Fax: +86-21-6425-3299 ;
Tel: +86-21-6425-3299
b
Shanghai Key Laboratory of New Drug Design, School of Pharmacy, and State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, P.R.China
c
Department of Chemistry & Chemical Biology, University of New Mexico, MSC03 2060, Albuquerque, USA
E-mail: wwang@unm.edu;
Fax: +1-505-277-2609 ;
Tel: +1-505-277-0756
Chem. Commun., 2013,49, 4667-4669

DOI: 10.1039/C3CC42216J
Received 26 Mar 2013, Accepted 02 Apr 2013
First published online 03 Apr 2013
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