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Issue 45, 2013
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Facile preparation of ordered mesoporous silica–carbon composite nanoparticles for glycan enrichment

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Abstract

Silica–carbon composite nanoparticles (NP-MCM-C) with uniform shapes and highly ordered mesoporous structures are directly prepared by using template polymers as the carbon source. And, taking advantage of the size exclusion effect of the mesopores to proteins and the specific interaction between carbon and oligosaccharides, the prepared nanoparticles are utilized to enrich N-linked glycans from complex biological samples with high selectivity and efficiency.

Graphical abstract: Facile preparation of ordered mesoporous silica–carbon composite nanoparticles for glycan enrichment

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Publication details

The article was received on 26 Feb 2013, accepted on 15 Apr 2013 and first published on 15 Apr 2013


Article type: Communication
DOI: 10.1039/C3CC41479E
Citation: Chem. Commun., 2013,49, 5162-5164
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    Facile preparation of ordered mesoporous silica–carbon composite nanoparticles for glycan enrichment

    H. Qin, Z. Hu, F. Wang, Y. Zhang, L. Zhao, G. Xu, R. Wu and H. Zou, Chem. Commun., 2013, 49, 5162
    DOI: 10.1039/C3CC41479E

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