Jump to main content
Jump to site search

Issue 32, 2013
Previous Article Next Article

A cascade approach to fused indolizinones through Lewis acid–copper(I) relay catalysis

Author affiliations

Abstract

A relay catalytic cascade process involving Lewis acid triggered ring-opening of cyclopropyl ketones with nitriles, the copper(I)-catalyzed Ritter process, and acid-promoted N-acyliminium ion cyclization is described, which efficiently provides thieno-, furano-, and benzo-indolizinones in moderate to good yields.

Graphical abstract: A cascade approach to fused indolizinones through Lewis acid–copper(i) relay catalysis

Back to tab navigation

Supplementary files

Publication details

The article was received on 25 Jan 2013, accepted on 05 Mar 2013 and first published on 06 Mar 2013


Article type: Communication
DOI: 10.1039/C3CC40643A
Citation: Chem. Commun., 2013,49, 3351-3353
  •   Request permissions

    A cascade approach to fused indolizinones through Lewis acid–copper(I) relay catalysis

    H. Huang, X. Ji, W. Wu and H. Jiang, Chem. Commun., 2013, 49, 3351
    DOI: 10.1039/C3CC40643A

Search articles by author

Spotlight

Advertisements