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Issue 31, 2013
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Reactions of organolithiums with dialkyl oxalates. A flow microreactor approach to synthesis of functionalized α-keto esters

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Abstract

Reactions of functionalized aryllithiums with dialkyl oxalates were achieved using a flow microreactor to obtain α-keto esters with high selectivity by virtue of fast 1 : 1 micromixing.

Graphical abstract: Reactions of organolithiums with dialkyl oxalates. A flow microreactor approach to synthesis of functionalized α-keto esters

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Publication details

The article was received on 17 Jan 2013, accepted on 28 Feb 2013, published on 13 Mar 2013 and first published online on 13 Mar 2013


Article type: Communication
DOI: 10.1039/C3CC40392K
Citation: Chem. Commun., 2013,49, 3242-3244
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    Reactions of organolithiums with dialkyl oxalates. A flow microreactor approach to synthesis of functionalized α-keto esters

    A. Nagaki, D. Ichinari and J. Yoshida, Chem. Commun., 2013, 49, 3242
    DOI: 10.1039/C3CC40392K

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