Centre for Molecular Nanometrology, West CHEM, Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral St., Glasgow, UK
; Tel: +44 (0)141 548 2507
Chem. Commun., 2013,49, 3206-3208
15 Jan 2013,
06 Mar 2013
First published online
14 Mar 2013
A novel method for analysing the catalytic action of a DNAzyme is reported. Resonance Raman scattering (RRS) is shown to successfully monitor the oxidation of two different peroxidase substrates and has been implemented in an assay for the detection of target DNA, providing a more sensitive method of analysis than current colorimetric techniques.
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