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Issue 31, 2013
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Resonance Raman scattering of catalytic beacons for DNA detection

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Abstract

A novel method for analysing the catalytic action of a DNAzyme is reported. Resonance Raman scattering (RRS) is shown to successfully monitor the oxidation of two different peroxidase substrates and has been implemented in an assay for the detection of target DNA, providing a more sensitive method of analysis than current colorimetric techniques.

Graphical abstract: Resonance Raman scattering of catalytic beacons for DNA detection

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Publication details

The article was received on 15 Jan 2013, accepted on 06 Mar 2013 and first published on 14 Mar 2013


Article type: Communication
DOI: 10.1039/C3CC40346G
Citation: Chem. Commun., 2013,49, 3206-3208
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    Resonance Raman scattering of catalytic beacons for DNA detection

    K. S. McKeating, D. Graham and K. Faulds, Chem. Commun., 2013, 49, 3206
    DOI: 10.1039/C3CC40346G

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