Maleimide-functionalised Pt(IV) complexes with highly selective binding properties to thiol groups were synthesised as precursors for binding of thiol-containing tumour-targeting molecules like human serum albumin.
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Maleimide-functionalised platinum(IV) complexes as a synthetic platform for targeted drug delivery
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a
University of Vienna, Institute of Inorganic Chemistry, Waehringer Strasse 42, Vienna, Austria
E-mail: christian.kowol@univie.ac.at ;
Fax: +43-1-4277-52680 ;
Tel: +43-1-4277-52609
E-mail: christian.kowol@univie.ac.at ;
Fax: +43-1-4277-52680 ;
Tel: +43-1-4277-52609
b
Research Platform “Translational Cancer Therapy Research” University of Vienna, Waehringer Strasse 42, Vienna, Austria
c
Institute of Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, Vienna, Austria
E-mail: petra.heffeter@meduniwien.ac.at ;
Fax: +43-1-40160-957555 ;
Tel: +43-1-40160-57557
E-mail: petra.heffeter@meduniwien.ac.at ;
Fax: +43-1-40160-957555 ;
Tel: +43-1-40160-57557
d
Department of Inorganic and Analytical Chemistry, University of Szeged, Dóm tér 7., H-6720 Szeged, Hungary
e
Division of Analytical Chemistry, Department of Chemistry, University of Natural Resources and Applied Life Sciences, Muthgasse 18, A-1190 Vienna, Austria
Chem. Commun., 2013,49, 2249-2251
DOI: 10.1039/C3CC39258A
Received 28 Dec 2012, Accepted 31 Jan 2013
First published online 01 Feb 2013
Chemical Communications
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