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Issue 22, 2013
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Efficient quenching of electrochemiluminescence from K-doped graphene–CdS:Eu NCs by G-quadruplex–hemin and target recycling-assisted amplification for ultrasensitive DNA biosensing

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Abstract

Based on the K-doped graphene–CdS:Eu NC composites and the nicking endonuclease (NEase) assisted strand-scission cycle, we have developed an ultrasensitive and selective electrochemiluminescence (ECL) DNA biosensor using the G-quadruplex–hemin-based DNAzyme which acts as an electrocatalyst for the reduction of H2O2, the coreactant of CdS:Eu NCs ECL.

Graphical abstract: Efficient quenching of electrochemiluminescence from K-doped graphene–CdS:Eu NCs by G-quadruplex–hemin and target recycling-assisted amplification for ultrasensitive DNA biosensing

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Publication details

The article was received on 17 Dec 2012, accepted on 01 Feb 2013 and first published on 01 Feb 2013


Article type: Communication
DOI: 10.1039/C3CC38990A
Citation: Chem. Commun., 2013,49, 2246-2248
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    Efficient quenching of electrochemiluminescence from K-doped graphene–CdS:Eu NCs by G-quadruplex–hemin and target recycling-assisted amplification for ultrasensitive DNA biosensing

    H. Zhou, Y. Zhang, J. Liu, J. Xu and H. Chen, Chem. Commun., 2013, 49, 2246
    DOI: 10.1039/C3CC38990A

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