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Highly diastereoselective synthesis of 3-indolylglycines via an asymmetric oxidative heterocoupling reaction of a chiral nickel(II) complex and indoles

Daizong Lin,a   Jiang Wang,a   Xu Zhang,ab   Shengbin Zhou,a   Jie Lian,ab   Hualiang Jianga and   Hong Liu*ab  
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a
State Key Laboratory of Drug Research, CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, P. R. China
E-mail: hliu@mail.shcnc.ac.cn
b
Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, P. R. China
Chem. Commun., 2013,49, 2575-2577

DOI: 10.1039/C3CC38908A
Received 13 Dec 2012, Accepted 05 Feb 2013
First published online 06 Feb 2013
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