Intracellular glutathione-triggered doxorubicin release from silica nanotubes with hydrophobic labile cap was demonstrated for the drug-resistant cancer cell treatment.
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Hydrophobic end-gated silica nanotubes for intracellular glutathione-stimulated drug delivery in drug-resistant cancer cells
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Corresponding authors
a
Department of Chemistry, Gachon University, Seongnam, Korea
E-mail: sjson@gachon.ac.kr
E-mail: sjson@gachon.ac.kr
b
Department of Chemistry, Soongsil University, Seoul 156-743, Korea
E-mail: sjoo@ssu.ac.kr
E-mail: sjoo@ssu.ac.kr
c
School of Integrative Engineering, Chung-Ang University, Seoul 156-756, Korea
d
Laboratory of Pharmacology, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea
e
Department of Chemistry & Biochemistry, University of Maryland, College Park, USA
E-mail: slee@umd.edu
E-mail: slee@umd.edu
f
Graduate School of Nanoscience and Technology (WCU), Korea Advance Institute of Science and Technology, Daejeon 305-701, Korea
Chem. Commun., 2013,49, 3194-3196
DOI: 10.1039/C3CC38761E
Received 06 Dec 2012, Accepted 06 Feb 2013
First published online 06 Feb 2013
Chemical Communications
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