The synthesis of small molecule based 1,3,5-trisubstituted benzenes for photo-mediated capture of human carbonic anhydrase II with visualisation by fluorescence is described.
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1,3,5-Trisubstituted benzenes as fluorescent photoaffinity probes for human carbonic anhydrase II capture
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a
Department of Chemistry, Indian Institute of Technology, Kharagpur 721302, India
E-mail: absk@chem.iitkgp.ernet.in ;
Fax: +91 3222 282552 ;
Tel: +91 3222 283300
E-mail: absk@chem.iitkgp.ernet.in ;
Fax: +91 3222 282552 ;
Tel: +91 3222 283300
b
Department of Biotechnology, Indian Institute of Technology, Kharagpur 721302, India
c
Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, UK
Chem. Commun., 2013,49, 1930-1932
DOI: 10.1039/C3CC38251F
Received 15 Nov 2012, Accepted 17 Jan 2013
First published online 17 Jan 2013
Chemical Communications
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