A method for caging a target protein with steric regulator molecules was developed to enable simple, strict, light-induced control of protein activity.
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Sterically bulky caging for light-inducible protein activation
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a
Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan
b
Department of Bioengineering, School of Engineering, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan
E-mail: yamaguchi@bio.t.u-tokyo.ac.jp ;
Fax: +81 (0)3 5841 8657 ;
Tel: +81 (0)3 5841 7328
E-mail: yamaguchi@bio.t.u-tokyo.ac.jp ;
Fax: +81 (0)3 5841 8657 ;
Tel: +81 (0)3 5841 7328
Chem. Commun., 2013,49, 3013-3015
DOI: 10.1039/C3CC38026B
Received 06 Nov 2012, Accepted 25 Feb 2013
First published online 25 Feb 2013
Chemical Communications
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