Jump to main content
Jump to site search

Issue 37, 2013
Previous Article Next Article

Asymmetric organocatalysis mediated by α,α-L-diaryl prolinols: recent advances

Author affiliations

Abstract

This feature article illustrates progress in asymmetric organocatalysis achieved by using readily available α,α-L-diaryl prolinols from 2009 up to middle 2012. This class of bifunctional organocatalysts has shown the ability to catalyze a variety of reactions such as epoxidation, cyclopropanation, α-sulfenylation of active methines, cross conjugate addition, direct aldol, cycloaddition and desymmetrization reactions. The most striking feature of these promoters is to enable either non-covalent or covalent activation of the reagents, thus distinguishing themselves as a rare example of organic promoters capable of encompassing alternative mechanistic pathways, namely enamine/iminium catalysis and Brønsted acid/base catalysis.

Graphical abstract: Asymmetric organocatalysis mediated by α,α-l-diaryl prolinols: recent advances

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 24 Sep 2012, accepted on 13 Mar 2013 and first published on 14 Mar 2013


Article type: Feature Article
DOI: 10.1039/C3CC36928E
Citation: Chem. Commun., 2013,49, 3821-3832
  •   Request permissions

    Asymmetric organocatalysis mediated by α,α-L-diaryl prolinols: recent advances

    S. Meninno and A. Lattanzi, Chem. Commun., 2013, 49, 3821
    DOI: 10.1039/C3CC36928E

Search articles by author