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Issue 24, 2013
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Branched peptideboronic acids (BPBAs): a novel mode of binding towards RNA

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Abstract

We report branched peptideboronic acids (BPBAs) that bind to RRE IIB from an on-bead high-throughput screening of a 3.3.4-library (46 656 compounds). We demonstrate that boronic acids are tunable moieties that afford a novel binding mode towards RNA.

Graphical abstract: Branched peptideboronic acids (BPBAs): a novel mode of binding towards RNA

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Publication details

The article was received on 10 Jan 2013, accepted on 07 Feb 2013 and first published on 07 Feb 2013


Article type: Communication
DOI: 10.1039/C3CC00243H
Citation: Chem. Commun., 2013,49, 2436-2438
  • Open access: Creative Commons BY-NC license
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    Branched peptideboronic acids (BPBAs): a novel mode of binding towards RNA

    W. Zhang, D. I. Bryson, J. B. Crumpton, J. Wynn and W. L. Santos, Chem. Commun., 2013, 49, 2436
    DOI: 10.1039/C3CC00243H

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