Silk scaffolds having biomimetic hierarchical porous structures were achieved by carefully tuning liquid–liquid separation in regenerated silk fibroin solutions. Such scaffolds show greatly enhanced cellular responses.
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Design and engineering of silk fibroin scaffolds with biomimetic hierarchical structures
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a
College of Materials, Xiamen University, China, Singapore
E-mail: phyliuxy@nus.edu.sg ;
Tel: +65 6516 2812
E-mail: phyliuxy@nus.edu.sg ;
Tel: +65 6516 2812
b
National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, China
c
Department of Orthopaedic Surgery, National University of Singapore, Singapore
d
College of Material Science and Engineering & State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Donghua University, Shanghai, China
Chem. Commun., 2013,49, 1431-1433
DOI: 10.1039/C2CC38779D
Received 24 Sep 2012, Accepted 18 Dec 2012
First published online 19 Dec 2012
Chemical Communications
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