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Issue 14, 2013
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Direct access to pyrazolo(benzo)thienoquinolines. Highly effective palladium catalysts for the intramolecular C–H heteroarylation of arenes

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Abstract

A short and atom-efficient strategy to obtain a series of pyrazolo(benzo)thienoquinolines is developed. Alternative catalytic systems for the key intramolecular direct heteroarylation of arenes are presented and include the first example of C–H (hetero)arylation of (hetero)arenes catalyzed by very low catalyst loadings of a palladium source.

Graphical abstract: Direct access to pyrazolo(benzo)thienoquinolines. Highly effective palladium catalysts for the intramolecular C–H heteroarylation of arenes

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Publication details

The article was received on 29 Aug 2012, accepted on 02 Jan 2013 and first published on 03 Jan 2013


Article type: Communication
DOI: 10.1039/C2CC37905H
Citation: Chem. Commun., 2013,49, 1413-1415
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    Direct access to pyrazolo(benzo)thienoquinolines. Highly effective palladium catalysts for the intramolecular C–H heteroarylation of arenes

    F. Churruca, S. Hernández, M. Perea, R. SanMartin and E. Domínguez, Chem. Commun., 2013, 49, 1413
    DOI: 10.1039/C2CC37905H

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