A highly sensitive gold nanoparticle-based colorimetric probe for pyrophosphate using a competition assay approach

Sudeok Kim; Min Sik Eom; Seung Kyung Kim; Seong Hyeok Seo; Min Su Han

doi:10.1039/C2CC37379C

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Chemical Communications

Issue 2, 2013

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A highly sensitive gold nanoparticle-based colorimetric probe for pyrophosphate using a competition assay approach

Sudeok Kim,^a Min Sik Eom,^a Seung Kyung Kim,^a Seong Hyeok Seo^a and Min Su Han*^a

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Department of Chemistry, Chung-Ang University, Seoul 156-756, Republic of Korea
E-mail: mshan@cau.ac.kr ;
Fax: +82-2-825-4736 ;
Tel: +82-2-820-5198

Chem. Commun., 2013,49, 152-154

DOI: 10.1039/C2CC37379C
Received 03 Sep 2012, Accepted 05 Nov 2012
First published online 20 Nov 2012

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In this study, a mixture of [Zn₂(1,3-bis[bis(2-pyridylmethyl)aminomethyl]benzene)]⁴⁺ ([Zn₂(BBPAB)]⁴⁺) and 11-mercaptoundecylphosphoric acid functionalized gold nanoparticles (Phos-AuNPs) is shown to be a highly sensitive colorimetric probe that can easily detect pyrophosphate (PPi) at less than 200 nM with the naked eye.

Abstract from Analytical Abstracts 2013

In this study, a mixture of (Zn₂(1,3-bis(bis(2-pyridylmethyl)aminomethyl)benzene))⁴⁺ ((Zn₂(BBPAB))⁴⁺) and 11-mercaptoundecylphosphoric acid functionalized gold nanoparticles (Phos-AuNPs) is shown to be a highly sensitive colorimetric probe that can easily detect pyrophosphate (PPi) at less than 200 nM with the naked eye.

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Sudeok Kim
Min Sik Eom
Seung Kyung Kim
Seong Hyeok Seo
Min Su Han

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