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Issue 39, 2013
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A disulfide-linked conjugate of ferrocenyl chalcone and silicon(IV) phthalocyanine as an activatable photosensitiser

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Abstract

A novel bis(ferrocenyl chalcone) silicon(IV) phthalocyanine has been prepared in which the disulfide linker can be cleaved by dithiothreitol. The separation of the ferrocenyl quencher and the phthalocyanine core greatly enhances the fluorescence emission, singlet oxygen production and in vitro photocytotoxicity.

Graphical abstract: A disulfide-linked conjugate of ferrocenyl chalcone and silicon(iv) phthalocyanine as an activatable photosensitiser

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Publication details

The article was received on 04 Oct 2012, accepted on 24 Oct 2012 and first published on 07 Nov 2012


Article type: Communication
DOI: 10.1039/C2CC37251G
Citation: Chem. Commun., 2013,49, 4274-4276
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    A disulfide-linked conjugate of ferrocenyl chalcone and silicon(IV) phthalocyanine as an activatable photosensitiser

    J. T. F. Lau, X. Jiang, D. K. P. Ng and P. Lo, Chem. Commun., 2013, 49, 4274
    DOI: 10.1039/C2CC37251G

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