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Issue 2, 2013
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An efficient single-enzymatic cascade for asymmetric synthesis of chiral amines catalyzed by ω-transaminase

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Abstract

An efficient single-enzymatic cascade approach for the asymmetric synthesis of chiral amines has been developed, which applies the amino donor 3-aminocyclohexa-1,5-dienecarboxylic acid spontaneously tautomerizing to reach reaction completion with excellent ee values.

Graphical abstract: An efficient single-enzymatic cascade for asymmetric synthesis of chiral amines catalyzed by ω-transaminase

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Publication details

The article was received on 03 Oct 2012, accepted on 07 Nov 2012 and first published on 08 Nov 2012


Article type: Communication
DOI: 10.1039/C2CC37232K
Citation: Chem. Commun., 2013,49, 161-163
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    An efficient single-enzymatic cascade for asymmetric synthesis of chiral amines catalyzed by ω-transaminase

    B. Wang, H. Land and P. Berglund, Chem. Commun., 2013, 49, 161
    DOI: 10.1039/C2CC37232K

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