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An immobilized and reusable Cu(I) catalyst for metal ion-free conjugation of ligands to fully deprotected oligonucleotides through click reaction

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Drug Discovery, Alnylam Pharmaceuticals, 300 Third Street, Cambridge, USA
E-mail: mmanoharan@alnylam.com;
Fax: +1 617-551-8101 ;
Tel: +1 617-551-8319
Chem. Commun., 2013,49, 184-186

DOI: 10.1039/C2CC36811K
Received 18 Sep 2012, Accepted 05 Nov 2012
First published online 21 Nov 2012
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