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Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, USA
E-mail: mallen@chem.wayne.edu
; Fax: +1 313 577 8822
; Tel: +1 313 577 2070
Chem. Commun., 2013,49, 4148-4150
DOI:
10.1039/C2CC36583A
Received
11 Sep 2012,
Accepted
18 Oct 2012
First published online
09 Nov 2012
A multimodal, β-amyloid-targeted contrast agent was synthesized and studied in vitro. The agent has a higher relaxivity than a clinically approved contrast agent and interacts with β-amyloid aggregates producing changes in relaxation rate and fluorescence emission.
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