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Issue 23, 2013
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Glucose selective Surface Plasmon Resonance-based bis-boronic acid sensor

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Abstract

Saccharides – a versatile class of biologically important molecules – are involved in a variety of physiological and pathological processes, but their detection and quantification is challenging. Herein, surface plasmon resonance and self-assembled monolayers on gold generated from bis-boronic acid bearing a thioctic acid moiety, whose intramolecular distance between the boronic acid moieties is well defined, are shown to detect D-glucose with high selectivity, demonstrating a higher affinity than other saccharides probed, namely D-galactose, D-fructose and D-mannose.

Graphical abstract: Glucose selective Surface Plasmon Resonance-based bis-boronic acid sensor

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Publication details

The article was received on 29 Apr 2013, accepted on 18 Sep 2013 and first published on 22 Oct 2013


Article type: Paper
DOI: 10.1039/C3AN01233F
Citation: Analyst, 2013,138, 7140-7145
  • Open access: Creative Commons BY license
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    Glucose selective Surface Plasmon Resonance-based bis-boronic acid sensor

    A. Stephenson-Brown, H. Wang, P. Iqbal, J. A. Preece, Y. Long, J. S. Fossey, T. D. James and P. M. Mendes, Analyst, 2013, 138, 7140
    DOI: 10.1039/C3AN01233F

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