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Issue 13, 2013
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A label-free amplified fluorescence DNA detection based on isothermal circular strand-displacement polymerization reaction and graphene oxide

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Abstract

A label-free fluorescent DNA biosensor has been presented based on isothermal circular strand-displacement polymerization reaction (ICSDPR) combined with graphene oxide (GO) binding. The proposed method is simple and cost-effective with a low detection limit of 4 pM, which compares favorably with other GO-based homogenous DNA detection methods.

Graphical abstract: A label-free amplified fluorescence DNA detection based on isothermal circular strand-displacement polymerization reaction and graphene oxide

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Publication details

The article was received on 01 Mar 2013, accepted on 30 Apr 2013 and first published on 30 Apr 2013


Article type: Communication
DOI: 10.1039/C3AN00421J
Citation: Analyst, 2013,138, 3616-3620
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    A label-free amplified fluorescence DNA detection based on isothermal circular strand-displacement polymerization reaction and graphene oxide

    Z. Li, W. Zhu, J. Zhang, J. Jiang, G. Shen and R. Yu, Analyst, 2013, 138, 3616
    DOI: 10.1039/C3AN00421J

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