Issue 13, 2013
From the journal:

Analyst

Turn-on selective vitamin B6 derivative fluorescent probe for histidine detection in biological samples†

Elisabete Oliveira,*ab   Carla Santos,a   Patrícia Poeta,b   José Luis Capeloa  and  Carlos Lodeiro*a  

* Corresponding authors

a BIOSCOPE group, REQUIMTE-CQFB, Chemistry Department, Faculty of Science and Technology, University NOVA of Lisbon, Monte de Caparica, Portugal
E-mail: cle@fct.unl.pt
Fax: +351 21 2948550
Tel: +351 21 2948300

b Veterinary Science Department, CECAV, University of Trás-os-Montes, Alto Douro, Vila Real, Portugal
E-mail: ejo14209@fct.unl.pt

Abstract

A new compound L soluble in water derived from vitamin B6 was successfully synthesized and characterized. The complex LAl3+ is a turn-on selective fluorescent probe for histidine in HEPES buffer, with detection and quantification limits of 0.3 μM and 0.6 μM, respectively. The application of the complex LAl3+ in real urine samples is reported.

Graphical abstract: Turn-on selective vitamin B6 derivative fluorescent probe for histidine detection in biological samples

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Article information

DOI
https://doi.org/10.1039/C3AN00324H
Article type
Communication
Submitted
15 Feb 2013
Accepted
19 Apr 2013
First published
23 Apr 2013

Analyst, 2013,138, 3642-3645

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Turn-on selective vitamin B6 derivative fluorescent probe for histidine detection in biological samples

E. Oliveira, C. Santos, P. Poeta, J. L. Capelo and C. Lodeiro, Analyst, 2013, 138, 3642 DOI: 10.1039/C3AN00324H

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