Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 13, 2013
Previous Article Next Article

Functionalised porous silicon as a biosensor: emphasis on monitoring cells in vivo and in vitro

Author affiliations

Abstract

Porous silicon photonics is the ideal platform for high sensitivity, high selectivity monitoring of biological molecules in a complex fluidic environment. The potential of this technology was identified almost 15 years ago, however, it has taken considerable advances in porous silicon surface chemistry, photonics, and micro-fabrication to create truly effective devices that can provide new insights into the behaviour of biological systems. In this review we provide a critical assessment of the development of porous silicon optical biosensors from the early demonstrations of affinity based sensing to the current trends in monitoring single cell activity and perspectives in the use of photonic microparticles for biomedical applications.

Graphical abstract: Functionalised porous silicon as a biosensor: emphasis on monitoring cells in vivo and in vitro

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 10 Jan 2013, accepted on 29 Apr 2013 and first published on 09 May 2013


Article type: Critical Review
DOI: 10.1039/C3AN00081H
Citation: Analyst, 2013,138, 3593-3615
  •   Request permissions

    Functionalised porous silicon as a biosensor: emphasis on monitoring cells in vivo and in vitro

    B. Gupta, Y. Zhu, B. Guan, P. J. Reece and J. J. Gooding, Analyst, 2013, 138, 3593
    DOI: 10.1039/C3AN00081H

Search articles by author